_1720416663 20240708090103000 Rovedar Daryoushbabazadeh@gmail.com Rovedar Journal of World’s Poultry Science J. World's Poult. Sci. 2980-7999 06 22 2024 3 2 Pimagha Moffo Hermann Joël https://orcid.org/0009-0003-7433-0117 Chongsi Margaret Mary Momo https://orcid.org/0000-0002-4422-8918 Tchouan Deffo Gilchrist https://orcid.org/0000-0002-4422-8918 Edie Nounamo Langston Wilfried https://orcid.org/0000-0002-3299-8966 Dongmo Nguedia Arius Baulland https://orcid.org/0000-0002-7219-572X Kana Jean Raphaël https://orcid.org/0000-0003-0767-4115 Introduction: The ban on the use of antibiotics as feed additives in livestock farming has led to the development of alternative products. This study aimed to evaluate the effects of combining phytobiotic (Dichrostachys glomerata) with a probiotic (Thepax®) on the growth performance of Japanese quails. Results: The findings indicated that quails fed on 0.6 ml probiotic / L of drinking water had the highest weight gain and the lowest feed conversion ratio. Combining phytobiotic with probiotics at 0.4 ml and 0.5 ml improved the apparent digestibility of crude protein and organic matter. Although the treatment did not significantly affect the carcass yields, the relative weight of the liver and pancreas were lowest with 0.4 ml probiotic. Haemato-biochemical parameters increased with higher levels of probiotics combined with 4 g of phytobiotics in the feed, leading to an increase in serum content in ALT and creatinine. Combining 4 g of the phytobiotic with 0.6 ml of probiotic resulted in a decrease in pathogens (Salmonella and E. coli) count in the gastrointestinal tract of quails. Conclusion: The combination of Dichrostachys glomerata (4g /kg feed) to a probiotic (0.6ml /L drinking water) improved feed conversion ratio and live weight gain while reducing the pathogenic microorganisms in the gastrointestinal tract of Japanese quails.   06 22 2024 26 32 https://creativecommons.org/licenses/by/4.0 10.58803/jwps.v3i2.30 https://jwps.rovedar.com/index.php/JWPS/article/view/30 https://jwps.rovedar.com/index.php/JWPS/article/download/30/57 https://jwps.rovedar.com/index.php/JWPS/article/download/30/57 10.4141/cjas2013-144 10.12816/0008247 Kana JR, Mube KH, Ngouana TR, Tsafong F, Komguep R, Yangoue A, et al. Effect of dietary mimosa small bell (Dichostachys glomerata) fruit supplement as alternative to antibiotic growth promoter for broiler chicken. Worlds Poult Sci J. 2017; 7(1): 27-34. Available at https://jwpr.science-line.com/attachments/article/40/J%20World%20Poult%20Res%207(1)%2027-34,%202017.pdf 10.11648/j.avs.20180605.13 10.1038/nrgastro.2014.66 10.58803/RBES.2023.2.1.01 10.1016/j.anifeedsci.2012.11.003 10.3390/ani11061620 Lessard M. Utilisation de probiotiques chez le porc- modulateurs potentiels de la santé intestinale [Use of probiotics in pigs - potential modulators of intestinal health]. Centre de référence en agriculture et agroalimentaire du Québec. 2004, p. 1-14. Available at: https://www.agrireseau.net/porc/documents/Lessard_Martin.pdf Ohimain E, and Ofongo R. The effect of probiotic and prebiotic feed supplementation on chicken health and gut microflora: A review. Int J Anim Veter Adv. 2012; 4: 135-143. Available at: https://maxwellsci.com/print/ijava/v4-135-143.pdf 10.3382/ps.2012-02813 Association of official analytical chemists (AOAC). Official methods of analysis. 15th edition. Washington, DC, USA: 1990. Available at: https://law.resource.org/pub/us/cfr/ibr/002/aoac.methods.1.1990.pdf 10.1016/j.psj.2020.04.019 10.30914/2411-9687-2022-8-2-150-159 10.1186/s12917-017-1160-y 10.3923/ijps.2020.539.547 Hasan MO, Abdulwahid AS, and Raouf SM. Effect of parsley seeds (Petroselinum Crispum) on physiological performance of Japanese quails. Iraqi J Poultry Sci. 2015; 9(2): 104-110. Available at: https://www.iasj.net/iasj/article/120570 10.15835/nsb919928 10.21608/zvjz.2021.97319.1158 10.21608/epsj.2021.160056 10.2141/jpsa.011089 10.25156/ptj.v10n1y2020.pp93-97