_1695542284 20230924075804000 Rovedar Daryoushbabazadeh@gmail.com Rovedar Journal of World’s Poultry Science J. World's Poult. Sci. 2980-7999 09 12 2023 2 3 Farzin KazemiLifshagerd Omid BehrouziNasab Alireza Koochakzadeh Majid Kazemnezhad Introduction: Giardia spp. are parasitic protozoans that infect the digestive system of ornamental birds, especially in Psittaciformes, with different prevalence in various species. Symptoms of Giardia infection vary from no noticeable signs in adult birds to poor growth, weakness, anorexia, ruffled feathers, and diarrhea in chicks. This study aimed to evaluate the prevalence of giardiasis in some parrots referred to a private veterinary clinic in Mashhad, Iran, during 2022. Case report: Feces of 215 birds suspected of being infected with Giardia spp. were collected. The birds were visited at one of the clinics in Mashhad, Iran, in 2022. Wet smear was prepared from their fresh feces and then sent to the laboratory department of the clinic for diagnosis. The parrots included adult cockatiels, cockatiel chicks, lovebirds, African grey parrots, and Green-cheeked parakeets. After the final diagnosis, metronidazole was administered orally at a dosage of 50 milligrams per kilogram of body weight every 12 hours for 5 consecutive days. Sick birds were tested again after the treatment to confirm they were parasite-free. The obtained results of the laboratory indicated 60 positive Cockatiels (47.6%), 10 positive cockatiel chicks (43.4%), 4 positive lovebirds (14.2%), 2 Green-cheeked parakeets (8.6%), and only 1 positive African grey parrot (6.6%). Among the positive cases, the severity of infection varied, with some birds showing severe, moderate, or mild infection levels. Upon a second examination, birds with mild and moderate contamination were found to be disease-free, while those with severe contamination required further treatment. Conclusion: The results suggested that treatment with metronidazole for 5 consecutive days was effective against mild to moderate infection in sick parrots. However, birds with severe conditions need to continue the treatment procedure. 09 12 2023 20 23 https://creativecommons.org/licenses/by/4.0 10.58803/jwps.v2i3.16 https://jwps.rovedar.com/index.php/JWPS/article/view/16 https://jwps.rovedar.com/index.php/JWPS/article/download/16/31 https://jwps.rovedar.com/index.php/JWPS/article/download/16/31 10.1016/j.meegid.2012.08.003 10.1017/S0031182015000049 10.1016/j.ijpara.2013.06.001 10.1201/9781315371047 Schmidt R, Reavill D, and Phalen D. Gastrointestinal system and pancreas. Pathology of pet and aviary birds. 2nd ed. John Wiley & Sons, Inc; 2003. p. 55-94. DOI: 10.1638/1042-7260(2003)034[0423:BR]2.0.CO;2 Hosseinian SA. Zoonotic diseases associated with pet birds. J Zoonotic Dis. 2022; 6(3): 91-112. DOI: 10.22034/jzd.2022.15461 10.1016/j.cvex.2009.06.009 10.1111/j.1751-0813.1998.tb10148.x 10.2307/3283880 10.1007/s00436-008-1293-9 Tully TN, Dorrestein GM, and Jones AK, editors. Handbook of avian medicine. New York: Elsevier, Saunders; 2009. Available at: https://cir.nii.ac.jp/crid/1130282272956430592 10.1100/2012/253127 10.1292/jvms1939.43.963 10.3390/ani11030801 Khalil N. Prevalence of Giardia spp in pet shop birds. J Vet.Res. 2018; 22(8): 736-738. Available at: https://www.cabdirect.org/cabdirect/abstract/20193021023