_1785385036 20260730041716000 Rovedar Daryoushbabazadeh@gmail.com Rovedar Journal of World’s Poultry Science J. World's Poult. Sci. 2980-7999 06 29 2026 5 2 Mohammad Abdalrahem Alhussen https://orcid.org/0009-0008-0716-3183 The increasing incorporation of antibiotics into poultry feed for growth development and disease prevention has resulted in serious health implications and the emergence of antimicrobial-resistant bacterial strains. The present study aimed to investigate the effects of ginger (Zingiber officinale) powder, as a dietary supplement, on immune response, gut integrity, total antioxidant capacity, and hematological and biochemical parameters in different poultry breeds. The present review examined 76 studies on the effects of dietary ginger on the health and physiology of poultry, including broiler and layer chickens, quail, and turkeys. Only peer-reviewed, indexed, full-text articles published in English were considered and investigated. Natural alternatives, such as ginger powder and its derivatives, in poultry production systems have been shown to mitigate antibiotic-related challenges and have been widely incorporated into poultry feed mixtures. Ginger supplementation in the feed of laying hens, broiler chickens, broiler chicks, and quail has enhanced intestinal integrity and increased the immune response against several viral diseases affecting poultry, such as Newcastle disease, infectious bursal disease, and avian influenza. Ginger has reduced glucose, triglycerides, and total cholesterol levels and increased high-density lipoprotein levels, thereby improving hematological parameters such as red blood cell count, hemoglobin, and packed cell volume, as well as kidney and liver functions. Ginger reduced oxidative stress and improved antioxidant status. Dietary ginger supplementation in poultry diets could serve as a natural feed additive to enhance growth, immunity, and overall health across poultry species, although optimal dosage may differ by species, age, and health status.   06 30 2026 28 35 https://creativecommons.org/licenses/by/4.0 10.58803/jwps.v5i2.129 https://jwps.rovedar.com/index.php/JWPS/article/view/129 https://jwps.rovedar.com/index.php/JWPS/article/download/129/129 https://jwps.rovedar.com/index.php/JWPS/article/download/129/129 10.1186/s41936-024-00379-5 10.1007/s11101-024-09994-0 10.1142/S0192415X22500410 10.3390/molecules27092826 10.1016/j.phanu.2017.01.001 10.21010/ajtcam.v13i6.11 10.3923/ijps.2012.143.146 Qorbanpour M, Fahim T, Javandel F, Nosrati M, Paz E, Seidavi A, et al. Effect of dietary (Zingiber officinale) and multi-strain probiotic on growth and carcass traits, blood biochemistry, immune responses and intestinal microflora in broiler chickens. Animals. 2018; 8(7): 117. 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